Genetic regulation of Caenorhabditis elegans lysosome related organelle function. High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis. Schwartz S, Agarwala SD, Mumbach MR, Jovanovic M, Mertins P, Shishkin A, Tabach Y, Mikkelsen TS, Satija R, Ruvkun G, Carr SA, Lander ES, Fink GR, Regev A. Multiple small RNA pathways regulate the silencing of repeated and foreign genes in C. PubMedįischer SE, Pan Q, Breen PC, Qi Y, Shi Z, Zhang C, Ruvkun G. MUT-14 and SMUT-1 DEAD box RNA helicases have overlapping roles in germline RNAi and endogenous siRNA formation. Phillips CM, Montgomery BE, Breen PC, Roovers EF, Rim YS, Ohsumi TK, Newman MA, van Wolfswinkel JC, Ketting RF, Ruvkun G, Montgomery TA. Caenorhabditis elegans pathways that surveil and defend mitochondria. Gene pathways that delay Caenorhabditis elegans reproductive senescence. Wang MC, Oakley HD, Carr CE, Sowa JN, Ruvkun G. PhyloGene server for identification and visualization of co-evolving proteins using normalized phylogenetic profiles. Sadreyev IR, Ji F, Cohen E, Ruvkun G, Tabach Y. elegans Genes from Misrouting into the RNAi Pathway. piRNAs and piRNA-Dependent siRNAs Protect Conserved and Essential C. Phillips CM, Brown KC, Montgomery BE, Ruvkun G, Montgomery TA. Lipid signalling couples translational surveillance to systemic detoxification in Caenorhabditis elegans. Govindan JA, Jayamani E, Zhang X, Breen P, Larkins-Ford J, Mylonakis E, Ruvkun G. coli free radical pathways and the mitochondria of C. Govindan JA, Jayamani E, Zhang X, Mylonakis E, Ruvkun G. Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1. elegans hypodermis couples to intestinal mTORC2/PQM-1 signaling to modulate fat transport. PubMedĭowen RH, Breen PC, Tullius T, Conery AL, Ruvkun G. DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity. Lin XX, Sen I, Janssens GE, Zhou X, Fonslow BR, Edgar D, Stroustrup N, Swoboda P, Yates JR, Ruvkun G, Riedel CG. The surveillance of pre-mRNA splicing is an early step in RNAi of endogenous genes. Newman MA, Ji F, Fischer SEJ, Anselmo A, Sadreyev RI, Ruvkun G. CarrierSeq: a sequence analysis workflow for low-input nanopore sequencing. Mojarro A, Hachey J, Ruvkun G, Zuber MT, Carr CE. Recent Molecular Genetic Explorations of MicroRNAs. Sequencing nothing: Exploring failure modes of nanopore sensing and implications for life detection. Pontefract A, Hachey J, Zuber MT, Ruvkun G, Carr CE. Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of. Tillman EJ, Richardson CE, Cattie DJ, Reddy KC, Lehrbach NJ, Droste R, Ruvkun G, Kim DH. Mitochondrial Dysfunction in C. elegans Activates Mitochondrial Relocalization and Nuclear Hormone Receptor-Dependent Detoxification Genes. Mao K, Ji F, Breen P, Sewell A, Han M, Sadreyev R, Ruvkun G. Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity. Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression. ROS-based lethality of mitochondrial electron transport mutants grown on siderophore iron release mutants. Lysosomal activity regulates mitochondrial dynamics through vitamin B12 metabolism.
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